Annual Activity Report 2025

Orano - Annual Activity Report 2025 135 SUSTAINABILITY STATEMENT 4 Societal and environmental challenges at the heart of the strategy 4.1.5 Significant Impacts, Risks and Opportunities and materiality of topics 4.1.5.1 Results of the materiality analysis The double materiality analysis, updated in 2025, identified 42 material Impacts, Risks and Opportunities (IRO) qualifying 22 material subtopics. These sub-topics are spread across all 10 existing topical ESRS standards. MATERIALITY OF THE SUB-TOPICS (2025) MATERIAL BY IMPACT ● Occupational health, safety, and radiation protection [S1] ● Working conditions and employee well-being [S1] ● Diversity and equal opportunities [S1] ● Working conditions for suppliers and subcontractors [S2] ● Economic development of territories [S3] ● Transparency and information for citizens [S4] ● Safety and security of our activities and products (health and safety of local residents) [S3] ● Climate change mitigation [E1] ● Freshwater [E3] ● Radioactive waste [E5] ● Skills and career development [S1] ● Continuity and cost for citizens [S4] ● Management of relationships with suppliers [G1] NON-MATERIAL BY IMPACT ● Energy [E1] ● Water and marine resources [E3] ● Pollution of air, water, and soil during operation [E2] ● Substances of concern and very high concern [E2] ● Impacts on the state of species [E4] ● Impacts on the extent and condition of ecosystems [E4] ● Direct operation (excluding water) [E4] ● Invasive alien species [E4] ● Circularity in inputs [E5] ● Hazardous and non-hazardous waste [E5] ● Disability [S1] ● Rights of Indigenous peoples [S3] ● Animal welfare [G1] ● Climate change adaptation [E1] ● Liabilities management and sites end-of-life [E2] ● Land-use change [E4] ● Circularity in products and services [E5] ● Social dialogue with trade unions [S1] ● Stakeholder dialogue and engagement [S3] ● Ethics and corporate culture [G1] ● Prevention of fraud, corruption, and influencepeddling [G1] ● Political dialogue and lobbying [G1] NON-MATERIAL BY FINANCE MATERIAL BY FINANCE The updates compared to the 2024 financial year take into account feedback, as well as a better adjustment of the topics to the Company organization. All IROs, formulations and quotes were reviewed. Among the main developments are: ● changes in the grouping of sub-topics: separation of “Ethics” and “Fraud prevention” topics, integration of “data security” topics into “Ethics and corporate culture” in order to better align with company policy; ● the “change of land use” sub-topic has been changed from double materiality to material by financial risk. This sub-topics materiality matrix was submitted for consultation to the social and economic committee (CSE in French) of Orano SA, in accordance with the obligation to consult the SEC provided for by French Order 2023-1142 of December 6, 2023, transposing the CSRD directive into French law. In accordance with the expectations of ESRS 2, IROs are expressed in gross impact and gross risk, before policies and actions carried out by the Company. They are presented in summary form at the beginning of the sustainability statement and in detail at the beginning of each thematic section. 4.1.5.2 Double materiality analysis methodology Scope of the double materiality analysis The double materiality analysis was carried out for the first time in 2024 according to the requirements of ESRS 2. It was updated using the scope of consolidation, as well as on the Upstream and Downstream value chain described in Section 4.1.3.1. Identification of sub-topics relevant to the analysis On the basis of AR 16 of ESRS 1 and sector analyses (benchmarking, analysis of non-financial rating agency grids, etc.), the group selected 35 topics at the start of the process. The “Microplastics [E2]” and “End-user safety [S4]” topics have been ruled out as irrelevant to the group’s current activities and its value chain. The sub-topics linked to the biodiversity pressure factors “Climate change”, “Water”, and “Pollution” have been dealt with in the associated topics (E1, E2 and E3). The sub-topics “Invasive alien

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